Announcements

Featured by the Wellcome–DBT India Alliance!

Prof. Ranjana Pathania and her research on small regulatory RNAs (sRNAs) are featured in the India Alliance’s “How I Got Here” series. The feature highlights her scientific journey and the lab’s work in advancing our understanding of sRNA-mediated regulation.

Read the full story on the India Alliance website: https://www.indiaalliance.org/stories_of_science/rna-series-ranjana-pathania

A recent research article titled "AI-enabled discovery of small molecule β-lactamase inhibitors to overcome enzyme diversity and resistance evolution" was published along with cover art in RSC Medicinal Chemistry by Perwez Bakht et al.

Our study, “Disruption of Cysteine Metabolism Leads to Synthetic Lethality and In Vivo Fitness Impairment in Acinetobacter baumannii” by Pathak A, Saini S, and Pathania R, published in mBio (2026), has been featured on ASM’s MicrobeTV.

Click on the link below and tune in to the engaging discussion of our research, starting at approximately 33:30.

https://www.microbe.tv/twim/twim-358/

Our recent discovery making headlines: Unveiling the role of LdtA in antibiotic resistance and pioneering novel strategies to combat bacterial evasion mechanisms

IIT-Roorkee Uncovers Groundbreaking Bacterial Resistance Mechanism Against UTI Treatments | Dehradun News - Times of IndiaA significant breakthrough by IIT-Roorkee researchers reveals a new bacterial resistance mechanism against mecillinam for UTI treatment, highlighting the potential of combining antibiotics with LdtA inhibitors to combat resistant E. coli infections.

IIT Roorkee's Discovery Offers Hope Against ResistantIn a ground-breaking development in the fight against antibiotic resistance, researchers at the Indian Institute of Technology Roorkee

IIT Roorkee researchers identify small molecule that can potentially fight against antibiotic-resistant pathogensThe new molecule, IITR08367, offers a ray of hope in treating antibiotic resistance in urinary tract infections and other ailments, a press release informed.

IIT Roorkee develops molecule to counter antibiotic resistance in UTIsIIT Roorkee researchers have discovered IITR08367, a molecule that combats antibiotic-resistant urinary tract infections (UTIs), particularly against Acinetobacter baumannii. This breakthrough promises to enhance the efficacy of existing antibiotics.

A recent research article on a novel effulx pump inhibitors of A. baumannii was published along with a cover art in ACS Infectious Diseases by Mahak Saini et. al.

A recent review on Cell-based screening to identify Cell wall targets of bacteria was published along with cover art by Rinki Gupta et. al.

Prof. Ranjana Pathania was featured as the reviewer of the month for Communications Biology (August 2023).

Research team at IIT-Roorkee discovers new antibacterial molecule | Dehradun News - Times of IndiaResearchers at the Indian Institute of Technology, Roorkee, discovered a new antibacterial small molecule -- IITR00693, that could help fight against

Interaction with Ambassador Hans Jacob Frydenlund from Norway regarding the research work of the Pathania Group

IIT Roorkee discovers unique approach to deal with blood infectionsResearchers from IIT Roorkee have discovered a molecule that targets Carbapenem resistance in bacterial pathogens.

IIT Roorkee Professor Awarded Senior Fellowship, to Work on Physiological Aspect of PathogensProf Ranjana Pathania of IIT Roorkee has been awarded the Senior Fellowship of the DBT-Welcome Trust India Alliance (2020-2021).

Novel molecule to combat multidrug-resistant bacteriaThe molecule identified by IIT Roorkee kills the bacteria by damaging the DNA and by inhibiting cell division

International Women’s day Celebrated on 8th March at UCOSTInternational Women’s day - Women has Proved them self on every era of Life and Profession. A Celebration at UCOST Dehradun

IIT Roorkee finds new drug target for antibiotic resistant bacteria Acinetobacter baumanniiIIT Roorkee researchers have identified the RNA protein Hfq as a potential drug target. Once the Hfq gene is removed, the Acinetobacter baumannii bacteria become less virulent, more susceptible to …

IIT Roorkee’s novel molecule reverses antibiotic resistanceThe small molecule used by Prof. Ranjana Pathania’s team at IIT Roorkee inhibits the proton gradient that drives the efflux pump leading to an effective build-up of antibiotic inside multidru…

IIT Roorkee organises 22nd ADNAT symposium - Express HealthcareThe symposium aimed to bring together scientists and academicians around the globe involved in antibiotic resistance research in healthcare and environmental settings

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